Thyroid hormones affect practically all organs in the body and control the organism's basal metabolism. The stomach and viscera are not spared, and thyroid dysfunction causes a variety of gastrointestinal symptoms, the true prevalence of which is unknown. Digestive symptoms or manifestations may also disclose thyroid disease clues, and if ignored or underestimated, diagnosis may be delayed, with dangerous consequences. Thyroid interactions with the gastrointestinal system have been widely recorded, however, there is no comprehensive report on the various effects of hypothyroidism in the literature. Although gastrointestinal motor dysfunction is largely acknowledged as the primary cause of symptoms, many complex phenomena remain unknown.
Hemorrhoids are a prevalent gastrointestinal condition that is being identified in general health screenings. Many clinical signs, such as asymptomatic piles or rectal bleeding, have a negative impact on quality of life.High intra-abdominal pressure and a fragile supporting structure are also risk factors for hemorrhoids. Obesity, constipation, diarrhea, chronic or persistent cough, pregnancy or delivery, and prolonged standing are all circumstances that might raise intra-abdominal pressure. Hypothyroidism manifests itself in a variety of organs and tissues. Constipation is the most prevalent gastrointestinal complaint in individuals with hypothyroidism, which can lead to hemorrhoids.
Recent research suggests that a thyroid hormone deficit causes the muscles that lining the digestive system to contract less forcefully. The accumulation of mucopolysaccharides, particularly hyaluronic acid, in the digestive tissue, which causes intestinal edema, is the most likely pathogenic cause. This decrease in motor activity lengthens the time that feces spend transiting through the digestive tract, allowing more water to be absorbed and finally leading to constipation that increases the intraluminal pressure, and causes compromisation of blood supply to the posterior anal wall and finally causes anal fissure.