RIYADH J FAKHRULDEEN
PhD. The Royal Society, Amman, Jordan.
The first use of Bromide as a treatment was for human epileptics over 200 years ago as or potassium bromide (KBr). Over the passage of time and the discovery of new anticonvulsants, KBr apparently became less popular due to the hepatotoxicity of bromide. Once in the brain, the bromide component becomes negatively charged ions and causes the brain cells to be also negatively charged. It is this negative state which seems to inhibit the excitability of neuron cells and helps to prevent the cells of the brain from firing in a random and haphazard manner