Jabir Raheem Hameed* and Ahmed Mohammed kohil@ *MB, ChB, FICMS, Consultant Plastic and Reconstructive Surgeon, Al-Sadr Teaching Hospital, Basrah. @MB, ChB, Candidate of CABMS Plastic and Reconstructive Surgery, Al-Sadr Teaching Hospital, Basrah, IRAQ. Abstract Keloid scar is one of the most challenging problems for physicians and surgeons. The current treatment of keloids is based on many ways and modalities which includes medical therapy, combined surgical excision with other modalities, physical treatment etc. The optimal curative treatment remains undefined. This study aimed to evaluate the effectiveness of the surgical excision combined with local infiltration of verapamil to treat patients with keloid. This prospective study involved 20 patients with keloid scars at different parts of the body. These keloid scars were surgically excised with local infiltration of Verapamil. This study was carried out at Al-Shaheed Ghazii Al-Harriri Hospital, Al-Wasity Hospital in Baghdad and Al-Sadr Teaching Hospital in Basrah Between January 2017 and May 2018. The age of the patients ranged between 11 to 44 years. Fourteen of them were females and 6 were males. After one year follow-up period, 11 patients had good results, 5 patients had moderate results and 4 patients had poor results. Patient’s satisfaction in those who had good results was excellent. No serious complications were recorded, only one patient got local wound dehiscence. In conclusion, surgical excision of keloid scar combined with post-surgical verapamil infiltration showed promising results in the management of keloid scar and reduction of its recurrence rate.