Ali Adnan Mohsin* & Sarkis K Strak@
*MBChB Registrar, @MBChB, MRCP, FRCP, Professor, Department of Medicine, University of Basrah, Basrah, IRAQ.
Experimental evidence supports a significant association between H. pylori infection and mosaic appearance of gastric mucosa. This study was carried out to find the significance of gastric mosaic mucosal pattern as a predictor of H. pylori related infection.
A total of one hundred consecutive patients were selected from those attending endoscopy unit at Al-Sader Teaching Hospital for various dyspeptic symptoms; fifty with mosaic gastric mucosa as patients and fifty with normal gastric mucosa as controls. They were classified according to their ages, gender, and smoking habits.
Two endoscopic biopsies from the antrum and corpus were taken from each patient and control and were tested for H. pylori by rapid urease test.
Mosaic gastric mucosal pattern was significantly associated with H. pylori infection, as compared with normal mucosa. Age was an important determinant for mosaic mucosal pattern and H. pylori infection, however; gender did not contribute to mosaic mucosal appearances and H. pylori infection, while smoking can contribute to mosaic mucosal appearance but not H. pylori infection.
In conclusion, mosaic mucosal pattern is a good indicator in predicting H. pylori related infection.