Cataract formation in the diabetic patients was studied on the basis of the determination of (Hb A1c%) using variant HPLC instrument and blood glucose enzymatic method for (42) blood specimens. These patients are; neglected blood glucose levels (patients are not using any treatment), on oral antidiabetic medications and insulin dependent. The effect of (Hb A1c %) when raise above the normal value (5.8%) in diabetic patients, is leading to disturb the transparency of the eye lens. The aim of this study is to show the relation between high values of (Hb A1c%) and cataract lens changes. (HbA1c%) of ten normal blood specimens were measured as control group.