Highly selective vagotomy accepted by increasing number of surgeons due to its low operative risk and relative lack of all side effects associated with other types of surgery like Truncal Vagotomy and drainage procedures. Our study concentrates on cases of chronic duodenal ulcer operations by H.S.V.regarding morbidity, mortality and recurrence rates. At Port General Hospital in Basrah and one private hospital over a period of twelve years from January 1991 to January 2002(H.S.V.) Highly selective vagotomy was performed on 100 cases of chronic duodenal ulcer (D.U.) which were diagnosed by endoscopy. All patients were followed for periods ranged between (24-120) months post operative morbidity and mortality were recorded. Visick grading was used to assess the post- operative clinical results, and endoscopy was done for all patients with visick grades III and IV. Seventy four(74) cases were uncomplicated and twenty six (26) were complicated ulcers (12 with obstruction, 10 with bleeding and 4 with perforation). Seventy two (72) cases were males and 28 cases were females. Their age ranged between (16-72) years. No major post- operative complication was recorded apart from one case who developed recurrent obstruction corrected by Finney pyloroplasty. Minor complications recorded were transient dysphagia (in 32 cases 32%) parasttic diarrhoea in eight (8) cases (8%), and some other non- related complications. Mortality was nil. (11 cases) were in Visick grade III and IV. Nine (9) cases of them were proved to have recurrent ulceration 89 cases were in visick grades I and II. My result shows that H.S.V. is a safe and effective procedure in the Management of uncomplicated and complicated chronic D.U. with less morbidity and mortality with accepted and medically controllable recurrence rate