Pancreatic cancer is the tenth most prevalent malignancy and the fifth most common cause of cancer death in the developed world. It was reported that less than 10% of patients survive for more than 1 year following diagnosis and the 5-year survival rate (0.4%), is the lowest of any cancer. This paper reflects authors experiences in pancreatic cancer and aimed to study pancreatic cancer clinically, determine the operative finding and outcome of surgical interference among our patients. Forty-five patients with pancreatic carcinoma were studied, 26(57.77%) patients were males, and 19(42.22%) patients were females, with males to females ratio of 1.36.Their age range from 27 to 80 years with an average of 58.7312.05 SD. The commonest risk factor was smoking occurred in 19(42.22%) patients, this was followed by diabetes mellitus occurred in 9(20%) patients. Jaundice was the commonest presenting symptom 32(72%) patients. Most cases were very advanced at time of diagnosis and only in one (3%) patient curative Whipple procedure was done. Tumor of the body of pancreas was very much infrequent than the head of pancreas was seen in 6 (13.3%) patients. From the patients that could follow up, non- survived for a one year.